Bilateral primary renal non-hodgki’s lymphoma presenting with acute renal failure: Successful treatment with systemic chemotherapy

Jin Hyuk Choi, Gyu Bog Choi, Ki Nam Shim, Sun Hee Sung, Woon Sup Han, Seung Yon Baek

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37 Scopus citations

Abstract

Primary renal non-Hodgkin’s lymphoma (NHL) with acute renal failure is a very rare condition, which frequently occurs in bilateral renal involvement. We report a 26-year-old male with primary bilateral renal NHL presenting with acute renal failure. A CT scan of the abdomen showed markedly enlarged kidneys with multinodularity and para-aortic lymphadenopathy. A percutaneous renal biopsy demonstrated ‘follicular center lymphoma, diffuse, small cell’. Thirteen cycles of systemic chemotherapy with cyclophosphamide-doxorubicin-vincristine-prednisolone (CHOP) and ifosfamide-methotrexate-etoposide-bleomycin (IMVP-Bleo) regimens were administered, which resulted in normalization of renal function with improvement of renal lymphoma. Since there was no further change of renal lesions after initial partial remission, a follow-up renal biopsy was performed 10 months after diagnosis, and no residual lymphoma was found.

Original languageEnglish
Pages (from-to)231-235
Number of pages5
JournalActa Haematologica
Volume97
Issue number4
DOIs
StatePublished - 1 Jan 1997

Keywords

  • Acute renal failure
  • Chemotherapy
  • Primary non-Hodgki’s lymphoma
  • Renal biopsy

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