Avian influenza-DNA hybridization detection using wavelength interrogation-based surface plasmon resonance biosensor

Shin Ae Kim, Sung June Kim, Kyung Min Byun, Sang Hun Lee, Tai Hyun Park, Sung Guk Kim, Michael L. Shuler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

A wavelength interrogation-based surface plasmon resonance (SPR) biosensor has been investigated for a detection of avian influenza DNA (AI-DNA). The hybridization reaction between AI-DNA and the immobilized oligonucleotide probe on a gold surface was monitored. The results showed that SPR biosensor can provide a linear detection suitable for quantification of AI-DNA hybridization as well as a large dynamic range. The experimental results were consistent well with numerical calculations using rigorous-coupled-wave analysis (RCWA). This study demonstrates the potential of using wavelength-scanning type SPR biosensor in a simple and real-time detection of AI virus.

Original languageEnglish
Title of host publicationIEEE Sensors 2009 Conference - SENSORS 2009
Pages832-835
Number of pages4
DOIs
StatePublished - 2009
EventIEEE Sensors 2009 Conference - SENSORS 2009 - Christchurch, New Zealand
Duration: 25 Oct 200928 Oct 2009

Publication series

NameProceedings of IEEE Sensors

Conference

ConferenceIEEE Sensors 2009 Conference - SENSORS 2009
Country/TerritoryNew Zealand
CityChristchurch
Period25/10/0928/10/09

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