Abstract
A chiral synthesis of functionalized benzo[a]quinolizine derivative (5) has been accomplished starting from a chiral lactone 7. The key feature is the efficient control of the stereochemistry of ring juncture of the functionalized benzo[a]quinolizine derivative 5 by the N-acyliminium ion cyclization of chiral lactam 11b.
Original language | English |
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Pages (from-to) | 3045-3056 |
Number of pages | 12 |
Journal | Tetrahedron |
Volume | 53 |
Issue number | 9 |
DOIs | |
State | Published - 3 Mar 1997 |
Bibliographical note
Funding Information:Acknowledgment. Financial support from the Korea Ministry of