The blaCMY-10 gene responsible for β-lactam resistance was located on a new complex class 1 integron within a conjugative plasmid. The sul1-type class 1 integron, containing an aadA2a gene cassette, was identified upstream of blaCMY-10. A unique gene array (yqgF-yqgE-gshB-orf97--orf105) was identified downstream of blaCMY-10..
Bibliographical noteFunding Information:
This work was supported by research grants from the Korea Research Foundation (KRF-2008-313-C00790), the Korea Science and Engineering Foundation (KOSEF), funded by the Korean Government (MEST) (2009-0077922), the Driving Force Project for the Next Generation of Gyeonggi Provincial Government in Korea, and the Marine & Extreme Genome Research Centre Program of Ministry of Land, Transport, and Maritime Affairs in Korea. The funding agencies had no role in the design or conduct of the study, analysis or interpretation of the data, or preparation, review or approval of the manuscript. The authors declare no conflict of interest concerning the funding agencies or a commercial company.
- Complex class 1 integron