Association between metabolic syndrome and gallbladder polyps in healthy Korean adults

Eun Jung Park, Hong Soo Lee, Sang Hwa Lee, Hye Jin Chun, Sun Young Kim, Yu Kyung Choi, Hee Jeong Ryu, Kyung Won Shim

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The goal of this study was to evaluate the association between gallbladder (GB) polyps and metabolic syndrome. A total of 5,685 healthy subjects were included, and 485 of these subjects had GB polyps and 744 had metabolic syndrome. In this study, metabolic syndrome was diagnosed according to standards suggested by the AHA/NHLBI ATP III 2005, and abdominal obesity ≥ 90 cm in men and ≥ 85 cm in women for Korean) was diagnosed according to standards set forth by the Korean Society for Study of Obesity. Biphasic logistic regression adjusted for age and gender was used to evaluate the association between metabolic syndrome and GB polyps. Subjects who were male (OR, 1.493; 95% CI, 1.11-2.00) and hepatitis B suface Ag (HBsAg) positive (OR, 1.591; 95% CI, 1.06-2.38) were significantly more likely to have GB polyps. The metabolic syndrome group had a higher risk of GB polyps (OR, 1.315; 95% CI, 1.01-1.69) than the group without metabolic syndrome. In conclusion, subjects who were HBsAg positive and male appear to be associated with the risk of GB polyps. The presence of metabolic syndrome also appears to be associated with the risk of GB polyps in Koreans.

Original languageEnglish
Pages (from-to)876-880
Number of pages5
JournalJournal of Korean Medical Science
Volume28
Issue number6
DOIs
StatePublished - Jun 2013

Keywords

  • GB polyp
  • Metabolic syndrome
  • Risk factors

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