Association between CHADS2, CHA2 DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients

Hyung Jun Kim, Moo Seok Park, Joonsang Yoo, Young Dae Kim, Hyungjong Park, Byung Moon Kim, Oh Young Bang, Hyeon Chang Kim, Euna Han, Dong Joon Kim, Joonnyung Heo, Jin Kyo Choi, Kyung Yul Lee, Hye Sun Lee, Dong Hoon Shin, Hye Yeon Choi, Sung Il Sohn, Jeong Ho Hong, Jong Yun Lee, Jang Hyun BaekGyu Sik Kim, Woo Keun Seo, Jong Won Chung, Seo Hyun Kim, Sang Won Han, Joong Hyun Park, Jinkwon Kim, Yo Han Jung, Han Jin Cho, Seong Hwan Ahn, Sung Ik Lee, Kwon Duk Seo, Yoonkyung Chang, Tae Jin Song, Hyo Suk Nam

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The CHADS2, CHA2 DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient. Results: Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS2 score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198–2.009, p = 0.001; CHA2 DS2 VASc score: OR 1.269, 95% CI 1.080–1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011–1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167–1.849, p = 0.001). The CHADS2 score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS2 score; 0.618, 95% CI 0.554–0.681). Conclusion: All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.

Original languageEnglish
Article number274
JournalJournal of Clinical Medicine
Volume11
Issue number1
DOIs
StatePublished - 1 Jan 2022

Keywords

  • Ischemic stroke
  • Recanalization
  • Stroke risk score
  • Thrombectomy

Fingerprint

Dive into the research topics of 'Association between CHADS2, CHA2 DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients'. Together they form a unique fingerprint.

Cite this