TY - JOUR
T1 - Ascending aortic diameter is associated with hypertension in Korean men
AU - Suh, Eunkyung
AU - Ryoo, Jae Hong
AU - Miae-Doo,
AU - Lee, Hong Soo
AU - Lee, Sang Wha
AU - Shim, Kyung Won
AU - Lee, Ju Young
AU - Ri Byun, A.
AU - Chun, Hyejin
N1 - Publisher Copyright:
© 2017 CIM.
PY - 2017
Y1 - 2017
N2 - Purpose: The purpose of this study was to evaluate the association between ascending aortic diameter (AAD) as measured with low-dose chest computed tomography (LDCT) and hypertension in Korean men. Methods: Korean men (n=1,050) who were screened for lung cancer using LDCT imaging at a health promotion center in Seoul, Korea between January 1 and December 31were recruited for the study. AAD is the longest length of ascending aorta measured from approximately 15 mm above left main coronary ostium to the mid-slice level of the right pulmonary artery. Results: AAD were divided into quartiles, and the degree of hypertension was determined based on the quartiles of the AAD using logistic regression. Odds ratios (OR) for the proportion of hypertension in Q2 (1.70, 95% CI: 1.11-2.59), Q3 (2.72, 95% CI: 1.81-4.09) and Q4 (3.94, 95% CI: 2.63-5.89) were significantly greater than that of Q1 (P for trend < 0.001). Even after controlling for confounding covariates of age, BMI, total cholesterol, HDL-cholesterol, fasting glucose, GGT, ALT, eGFR, smoking status and alcohol intake, there was significant correlation. Conclusion: AAD was significantly associated with the degree of hypertension.
AB - Purpose: The purpose of this study was to evaluate the association between ascending aortic diameter (AAD) as measured with low-dose chest computed tomography (LDCT) and hypertension in Korean men. Methods: Korean men (n=1,050) who were screened for lung cancer using LDCT imaging at a health promotion center in Seoul, Korea between January 1 and December 31were recruited for the study. AAD is the longest length of ascending aorta measured from approximately 15 mm above left main coronary ostium to the mid-slice level of the right pulmonary artery. Results: AAD were divided into quartiles, and the degree of hypertension was determined based on the quartiles of the AAD using logistic regression. Odds ratios (OR) for the proportion of hypertension in Q2 (1.70, 95% CI: 1.11-2.59), Q3 (2.72, 95% CI: 1.81-4.09) and Q4 (3.94, 95% CI: 2.63-5.89) were significantly greater than that of Q1 (P for trend < 0.001). Even after controlling for confounding covariates of age, BMI, total cholesterol, HDL-cholesterol, fasting glucose, GGT, ALT, eGFR, smoking status and alcohol intake, there was significant correlation. Conclusion: AAD was significantly associated with the degree of hypertension.
UR - http://www.scopus.com/inward/record.url?scp=85029391288&partnerID=8YFLogxK
U2 - 10.25011/cim.v40i4.28493
DO - 10.25011/cim.v40i4.28493
M3 - Article
C2 - 28875927
AN - SCOPUS:85029391288
SN - 0147-958X
VL - 40
SP - E158-E166
JO - Clinical and Investigative Medicine
JF - Clinical and Investigative Medicine
IS - 4
ER -