Abstract
Antigenicity of crude extracts of adult Spirometra erinacei was evaluated in comparison to those of the plerocercoid (sparganum) for serodiagnosis of human sparganosis. Patients' sera from 39 sparganosis, 77 other helminthic diseases, and 50 uninfected controls were tested by enzyme-linked immunosorbent assay (ELISA). When both extracts were used as antigen, specific antibody levels in sparganosis sera were highly correlated (r = 0.83). The sensitivity and specificity of the adult worm extracts were 92.3 and 98.3%, while those of the sparganum were 94.3 and 96.6%, respectively. This result showed that crude extracts of adult S. erinacei could be used as a diagnostic antigen of sparganosis.
| Original language | English |
|---|---|
| Pages (from-to) | 122-124 |
| Number of pages | 3 |
| Journal | Comparative Parasitology |
| Volume | 65 |
| Issue number | 1 |
| State | Published - 1998 |
Keywords
- Antigen
- Immunodiagnosis
- Sparganosis
- Sparganum
- Spirometra erinacei
