Antibody phage display

Hyunbo Shim

doi:10.1007/978-3-319-72077-7_2

Antibody phage display

Hyunbo Shim

Department of Life Science

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

21 Scopus citations

Abstract

Antibody phage display has become an indispensable tool for the discovery and optimization of target-specific monoclonal antibodies suitable for demanding applications including therapeutic reagents. The in vitro nature of the technology enables the rapid and efficient identification of specific binders, as well as greater control over selection parameters that facilitates the isolation of antibodies with unique, desirable functional characteristics. In this chapter, the technological background and the state of the art in the field of antibody phage display is discussed.

Original language	English
Title of host publication	Advances in Experimental Medicine and Biology
Publisher	Springer New York LLC
Pages	21-34
Number of pages	14
DOIs	https://doi.org/10.1007/978-3-319-72077-7_2
State	Published - 2017

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	1053
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

Bibliographical note

Publisher Copyright:
© Springer International Publishing AG, part of Springer Nature 2017.

Keywords

Antibody library
Bacteriophage
Fab
Immune antibody library
Natural antibody library
Phage display
ScFv
Synthetic antibody library

Access to Document

10.1007/978-3-319-72077-7_2

Cite this

@inbook{0b1e34f7106549a7ad1cbf539918ecd4,

title = "Antibody phage display",

abstract = "Antibody phage display has become an indispensable tool for the discovery and optimization of target-specific monoclonal antibodies suitable for demanding applications including therapeutic reagents. The in vitro nature of the technology enables the rapid and efficient identification of specific binders, as well as greater control over selection parameters that facilitates the isolation of antibodies with unique, desirable functional characteristics. In this chapter, the technological background and the state of the art in the field of antibody phage display is discussed.",

keywords = "Antibody library, Bacteriophage, Fab, Immune antibody library, Natural antibody library, Phage display, ScFv, Synthetic antibody library",

author = "Hyunbo Shim",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing AG, part of Springer Nature 2017.",

year = "2017",

doi = "10.1007/978-3-319-72077-7_2",

language = "English",

series = "Advances in Experimental Medicine and Biology",

publisher = "Springer New York LLC",

pages = "21--34",

booktitle = "Advances in Experimental Medicine and Biology",

}

TY - CHAP

T1 - Antibody phage display

AU - Shim, Hyunbo

N1 - Publisher Copyright: © Springer International Publishing AG, part of Springer Nature 2017.

PY - 2017

Y1 - 2017

N2 - Antibody phage display has become an indispensable tool for the discovery and optimization of target-specific monoclonal antibodies suitable for demanding applications including therapeutic reagents. The in vitro nature of the technology enables the rapid and efficient identification of specific binders, as well as greater control over selection parameters that facilitates the isolation of antibodies with unique, desirable functional characteristics. In this chapter, the technological background and the state of the art in the field of antibody phage display is discussed.

AB - Antibody phage display has become an indispensable tool for the discovery and optimization of target-specific monoclonal antibodies suitable for demanding applications including therapeutic reagents. The in vitro nature of the technology enables the rapid and efficient identification of specific binders, as well as greater control over selection parameters that facilitates the isolation of antibodies with unique, desirable functional characteristics. In this chapter, the technological background and the state of the art in the field of antibody phage display is discussed.

KW - Antibody library

KW - Bacteriophage

KW - Fab

KW - Immune antibody library

KW - Natural antibody library

KW - Phage display

KW - ScFv

KW - Synthetic antibody library

UR - http://www.scopus.com/inward/record.url?scp=85044261600&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-72077-7_2

DO - 10.1007/978-3-319-72077-7_2

M3 - Chapter

C2 - 29549633

AN - SCOPUS:85044261600

T3 - Advances in Experimental Medicine and Biology

SP - 21

EP - 34

BT - Advances in Experimental Medicine and Biology

PB - Springer New York LLC

ER -

Antibody phage display

Abstract

Publication series

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this