Abstract
Background: We evaluated the clinical efficacy and safety of the mixed solution of sodium hyaluronate and sodium carboxymethylcellulose (HA-CMC) for prevention of adhesion after endoscopic sinus surgery. Methods: Preoperative computed tomography (CT) scans were graded. At the completion of surgery, HA-CMC was applied to Merocel and repeatedly applied after the removal of Merocel. As a control, normal saline was applied. Endoscopic examination was performed postoperatively and grading was done. Results: The rate of adhesion was the highest at 2 weeks postoperatively and was significantly lower in the HA-CMC-treated group than the control on all postoperative days. The grouping of cases by CT scores at 2 weeks postoperatively showed lower adhesion formation with the HA-CMC treatment than the control. The safety profile of the patients was normal at 4 weeks postoperatively. Conclusion: HA-CMC is an efficacious and safe material in decreasing the incidence of adhesion after endoscopic sinus surgery.
Original language | English |
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Pages (from-to) | 95-99 |
Number of pages | 5 |
Journal | American Journal of Rhinology |
Volume | 21 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2007 |
Keywords
- Adhesion
- Endoscopic sinus surgery
- Postsurgical
- Revision surgery
- Sodium carboxymethylcellulose
- Sodium hyaluronate
- Surgical complication