Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis Associated With Mediastinal and Ovarian Teratomas: A Case Report

Sue Hyun Lee; Chan Young Lee; Heae Surng Park; Jin Park; Ji Young Yun

doi:10.3346/jkms.2023.38.e31

Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis Associated With Mediastinal and Ovarian Teratomas: A Case Report

Sue Hyun Lee, Chan Young Lee, Heae Surng Park, Jin Park, Ji Young Yun

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis. Approximately 80% of patients with anti-NMDAR encephalitis are women. Tumors are detected in approximately 50% of female patients with anti-NMDAR encephalitis, of which 96% are ovarian teratomas. We describe the case of a 28-year-old woman diagnosed with anti-NMDAR encephalitis with mediastinal and bilateral ovarian teratomas in July 2019. The patient recovered following surgical management of the mediastinal mass and both ovarian teratomas, and immunotherapy. This case shows that teratomas can be found at multiple sites other than ovaries.

Original language	English
Article number	e31
Journal	Journal of Korean Medical Science
Volume	38
Issue number	6
DOIs	https://doi.org/10.3346/jkms.2023.38.e31
State	Published - 2023

Bibliographical note

Funding Information:
This work was supported by the Ewha Womans University Research Grant of 2021 and the National Research Foundation of Korea (NRF) grant by the Korea government (Ministry of Science and ICT) (No. 2021R1G1A1095175).

Publisher Copyright:
© 2023 The Korean Academy of Medical Sciences

Keywords

Autoimmune EncephalitisTeratoma
NMDA Encephalitis

Access to Document

10.3346/jkms.2023.38.e31

Cite this

@article{0ad5f341c40b42ea9c721f7cabb7111e,

title = "Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis Associated With Mediastinal and Ovarian Teratomas: A Case Report",

abstract = "Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis. Approximately 80% of patients with anti-NMDAR encephalitis are women. Tumors are detected in approximately 50% of female patients with anti-NMDAR encephalitis, of which 96% are ovarian teratomas. We describe the case of a 28-year-old woman diagnosed with anti-NMDAR encephalitis with mediastinal and bilateral ovarian teratomas in July 2019. The patient recovered following surgical management of the mediastinal mass and both ovarian teratomas, and immunotherapy. This case shows that teratomas can be found at multiple sites other than ovaries.",

keywords = "Autoimmune EncephalitisTeratoma, NMDA Encephalitis",

author = "Lee, {Sue Hyun} and Lee, {Chan Young} and Park, {Heae Surng} and Jin Park and Yun, {Ji Young}",

note = "Funding Information: This work was supported by the Ewha Womans University Research Grant of 2021 and the National Research Foundation of Korea (NRF) grant by the Korea government (Ministry of Science and ICT) (No. 2021R1G1A1095175). Publisher Copyright: {\textcopyright} 2023 The Korean Academy of Medical Sciences",

year = "2023",

doi = "10.3346/jkms.2023.38.e31",

language = "English",

volume = "38",

journal = "Journal of Korean Medical Science",

issn = "1011-8934",

publisher = "Korean Academy of Medical Science",

number = "6",

}

TY - JOUR

T1 - Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis Associated With Mediastinal and Ovarian Teratomas

T2 - A Case Report

AU - Lee, Sue Hyun

AU - Lee, Chan Young

AU - Park, Heae Surng

AU - Park, Jin

AU - Yun, Ji Young

N1 - Funding Information: This work was supported by the Ewha Womans University Research Grant of 2021 and the National Research Foundation of Korea (NRF) grant by the Korea government (Ministry of Science and ICT) (No. 2021R1G1A1095175). Publisher Copyright: © 2023 The Korean Academy of Medical Sciences

PY - 2023

Y1 - 2023

N2 - Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis. Approximately 80% of patients with anti-NMDAR encephalitis are women. Tumors are detected in approximately 50% of female patients with anti-NMDAR encephalitis, of which 96% are ovarian teratomas. We describe the case of a 28-year-old woman diagnosed with anti-NMDAR encephalitis with mediastinal and bilateral ovarian teratomas in July 2019. The patient recovered following surgical management of the mediastinal mass and both ovarian teratomas, and immunotherapy. This case shows that teratomas can be found at multiple sites other than ovaries.

AB - Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis. Approximately 80% of patients with anti-NMDAR encephalitis are women. Tumors are detected in approximately 50% of female patients with anti-NMDAR encephalitis, of which 96% are ovarian teratomas. We describe the case of a 28-year-old woman diagnosed with anti-NMDAR encephalitis with mediastinal and bilateral ovarian teratomas in July 2019. The patient recovered following surgical management of the mediastinal mass and both ovarian teratomas, and immunotherapy. This case shows that teratomas can be found at multiple sites other than ovaries.

KW - Autoimmune EncephalitisTeratoma

KW - NMDA Encephalitis

UR - http://www.scopus.com/inward/record.url?scp=85148061522&partnerID=8YFLogxK

U2 - 10.3346/jkms.2023.38.e31

DO - 10.3346/jkms.2023.38.e31

M3 - Article

C2 - 36786082

AN - SCOPUS:85148061522

SN - 1011-8934

VL - 38

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

IS - 6

M1 - e31

ER -

Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis Associated With Mediastinal and Ovarian Teratomas: A Case Report

Abstract

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this