Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities

Yun Seo Kil, Sally T. Pham, Eun Kyoung Seo, Mahtab Jafari

Research output: Contribution to journalReview articlepeer-review

57 Scopus citations

Abstract

Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food. Various flavonoids, coumarins, phenolics, acetylenes, sesquiterpene, diterpene, and triterpenes were identified as the constituents of A. keiskei. The crude extracts and pure constituents were proven to inhibit tumor growth and ameliorate inflammation, obesity, diabetics, hypertension, and ulcer. The extract also showed anti-thrombotic, anti-oxidative, anti-hyperlipidemic, anti-viral, and anti-bacterial activities. This valuable herb needs to be further studied and developed not only to treat these human diseases but also to improve human health. Currently A. keiskei is commercialized as a health food and additives in health drinks. This article presents a comprehensive review of A. keiskei and its potential place in the improvement of human health.

Original languageEnglish
Pages (from-to)655-675
Number of pages21
JournalArchives of Pharmacal Research
Volume40
Issue number6
DOIs
StatePublished - 1 Jun 2017

Bibliographical note

Publisher Copyright:
© 2017, The Pharmaceutical Society of Korea.

Keywords

  • Angelica keiskei
  • Biological activity
  • Chemical constituent
  • Umbelliferae

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