TY - JOUR
T1 - Analysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from Korea
AU - Kim, Jae J.
AU - Reddy, Rita
AU - Lee, Miae
AU - Kim, Jong G.
AU - El-Zaatari, Fouad A.K.
AU - Osato, Michael S.
AU - Graham, David Y.
AU - Kwon, Dong H.
PY - 2001
Y1 - 2001
N2 - Antibiotic resistance in Helicobacter pylori varies according to geographical region. We studied the primary resistance rates among 652 H. pylori isolated from Korea in relation to collection date, disease presentation, age and gender. Resistance rates were 40.6% (metronidazole), 5.9% (clarithromycin), 5.3% (tetracycline), 0% (amoxycillin), 1.5% (furazolidone) and 1.5% (nitrofurantoin). Resistance to metronidazole and clarithromycin increased from 1994 to 1999 (from 33.3 to 47.7% and 4.8 to 7.7%, respectively), but the differences only reached significance when rates of metronidazole resistance in women were compared with those in men (48.6 versus 36.9%).
AB - Antibiotic resistance in Helicobacter pylori varies according to geographical region. We studied the primary resistance rates among 652 H. pylori isolated from Korea in relation to collection date, disease presentation, age and gender. Resistance rates were 40.6% (metronidazole), 5.9% (clarithromycin), 5.3% (tetracycline), 0% (amoxycillin), 1.5% (furazolidone) and 1.5% (nitrofurantoin). Resistance to metronidazole and clarithromycin increased from 1994 to 1999 (from 33.3 to 47.7% and 4.8 to 7.7%, respectively), but the differences only reached significance when rates of metronidazole resistance in women were compared with those in men (48.6 versus 36.9%).
UR - http://www.scopus.com/inward/record.url?scp=0035048039&partnerID=8YFLogxK
U2 - 10.1093/jac/47.4.459
DO - 10.1093/jac/47.4.459
M3 - Article
C2 - 11266421
AN - SCOPUS:0035048039
SN - 0305-7453
VL - 47
SP - 459
EP - 461
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
IS - 4
ER -
