An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

Nahyun Kwon; Myoung Ki Cho; Sang Jun Park; Dayoung Kim; Sang Jip Nam; Lei Cui; Hwan Myung Kim; Juyoung Yoon

doi:10.1039/C6CC08971B

An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

Nahyun Kwon
, Myoung Ki Cho
, Sang Jun Park
, Dayoung Kim
, Sang Jip Nam
, Lei Cui
, Hwan Myung Kim
, Juyoung Yoon

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.

Original language	English
Pages (from-to)	525-528
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	3
DOIs	https://doi.org/10.1039/C6CC08971B
State	Published - 2017

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry.

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/C6CC08971B

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title = "An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells",

abstract = "A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.",

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language = "English",

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journal = "Chemical Communications",

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AU - Kwon, Nahyun

AU - Cho, Myoung Ki

AU - Park, Sang Jun

AU - Kim, Dayoung

AU - Nam, Sang Jip

AU - Cui, Lei

AU - Kim, Hwan Myung

AU - Yoon, Juyoung

PY - 2017

Y1 - 2017

N2 - A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.

AB - A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.

UR - https://www.scopus.com/pages/publications/85008626088

U2 - 10.1039/C6CC08971B

DO - 10.1039/C6CC08971B

M3 - Article

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AN - SCOPUS:85008626088

SN - 1359-7345

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SP - 525

EP - 528

JO - Chemical Communications

JF - Chemical Communications

IS - 3

ER -

An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

Abstract

Bibliographical note

UN SDGs

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