An aryl-thioether substituted nitrobenzothiadiazole probe for the selective detection of cysteine and homocysteine

Dayoung Lee, Gyoungmi Kim, Jun Yin, Juyoung Yoon

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An aryl-thioether substituted nitrobenzothiadiazole probe was synthesized and employed to detect cysteine and homocysteine selectively in living cells. Interestingly, both cysteine (Cys) and homocysteine (Hcy) promote an enhancement of the fluorescence intensity of the probe at pH 7.4 while only Cys gives rise to this enhancement under weakly acidic conditions (pH 6.0).

Original languageEnglish
Pages (from-to)6518-6520
Number of pages3
JournalChemical Communications
Issue number30
StatePublished - 18 Apr 2015

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© The Royal Society of Chemistry 2015.

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