An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

Lei Cui, Yeonju Baek, Songyi Lee, Nahyun Kwon, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells.

Original languageEnglish
Pages (from-to)2909-2914
Number of pages6
JournalJournal of Materials Chemistry C
Volume4
Issue number14
DOIs
StatePublished - 14 Apr 2016

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