An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

Lei Cui; Yeonju Baek; Songyi Lee; Nahyun Kwon; Juyoung Yoon

doi:10.1039/c5tc03272e

An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

Lei Cui, Yeonju Baek, Songyi Lee, Nahyun Kwon, Juyoung Yoon

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Abstract

A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells.

Original language	English
Pages (from-to)	2909-2914
Number of pages	6
Journal	Journal of Materials Chemistry C
Volume	4
Issue number	14
DOIs	https://doi.org/10.1039/c5tc03272e
State	Published - 14 Apr 2016

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© The Royal Society of Chemistry 2016.

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abstract = "A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells.",

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AU - Cui, Lei

AU - Baek, Yeonju

AU - Lee, Songyi

AU - Kwon, Nahyun

AU - Yoon, Juyoung

PY - 2016/4/14

Y1 - 2016/4/14

N2 - A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells.

AB - A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells.

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DO - 10.1039/c5tc03272e

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EP - 2914

JO - Journal of Materials Chemistry C

JF - Journal of Materials Chemistry C

IS - 14

ER -

An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

Abstract

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