Advances in Narcolepsy Syndrome and Challenges in the Pediatric Population

Christian Guilleminault; Victoria Zvonkina; Visasiri Tantrakul; Jee Hyun Kim

doi:10.1016/j.jsmc.2007.05.005

Advances in Narcolepsy Syndrome and Challenges in the Pediatric Population

Christian Guilleminault, Victoria Zvonkina, Visasiri Tantrakul, Jee Hyun Kim

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Narcolepsy onset occurs most commonly in the second decade but presents a diagnostic challenge when it starts in prepubertal children. The diagnosis is particularly difficult to establish in very young individuals (<5 years of age). Clinical neurophysiologic tests are not very useful in such cases, and recent studies challenge the findings of Multiple Sleep Latency Tests administered to younger and older children. CSF dosage of hypocretin may be helpful. Advances and challenges in pediatric narcolepsy are presented in the report.

Original language	English
Pages (from-to)	397-404
Number of pages	8
Journal	Sleep Medicine Clinics
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/j.jsmc.2007.05.005
State	Published - Sep 2007

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10.1016/j.jsmc.2007.05.005

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title = "Advances in Narcolepsy Syndrome and Challenges in the Pediatric Population",

abstract = "Narcolepsy onset occurs most commonly in the second decade but presents a diagnostic challenge when it starts in prepubertal children. The diagnosis is particularly difficult to establish in very young individuals (<5 years of age). Clinical neurophysiologic tests are not very useful in such cases, and recent studies challenge the findings of Multiple Sleep Latency Tests administered to younger and older children. CSF dosage of hypocretin may be helpful. Advances and challenges in pediatric narcolepsy are presented in the report.",

author = "Christian Guilleminault and Victoria Zvonkina and Visasiri Tantrakul and Kim, \{Jee Hyun\}",

year = "2007",

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pages = "397--404",

journal = "Sleep Medicine Clinics",

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T1 - Advances in Narcolepsy Syndrome and Challenges in the Pediatric Population

AU - Guilleminault, Christian

AU - Zvonkina, Victoria

AU - Tantrakul, Visasiri

AU - Kim, Jee Hyun

PY - 2007/9

Y1 - 2007/9

N2 - Narcolepsy onset occurs most commonly in the second decade but presents a diagnostic challenge when it starts in prepubertal children. The diagnosis is particularly difficult to establish in very young individuals (<5 years of age). Clinical neurophysiologic tests are not very useful in such cases, and recent studies challenge the findings of Multiple Sleep Latency Tests administered to younger and older children. CSF dosage of hypocretin may be helpful. Advances and challenges in pediatric narcolepsy are presented in the report.

AB - Narcolepsy onset occurs most commonly in the second decade but presents a diagnostic challenge when it starts in prepubertal children. The diagnosis is particularly difficult to establish in very young individuals (<5 years of age). Clinical neurophysiologic tests are not very useful in such cases, and recent studies challenge the findings of Multiple Sleep Latency Tests administered to younger and older children. CSF dosage of hypocretin may be helpful. Advances and challenges in pediatric narcolepsy are presented in the report.

UR - https://www.scopus.com/pages/publications/57149105103

U2 - 10.1016/j.jsmc.2007.05.005

DO - 10.1016/j.jsmc.2007.05.005

M3 - Review article

AN - SCOPUS:57149105103

SN - 1556-407X

VL - 2

SP - 397

EP - 404

JO - Sleep Medicine Clinics

JF - Sleep Medicine Clinics

IS - 3

ER -

Advances in Narcolepsy Syndrome and Challenges in the Pediatric Population

Abstract

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