Adenovirus pneumonia treated with Cidofovir in an immunocompetent high school senior

Hee Young Yoon, Hyun Hae Cho, Yon Ju Ryu

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Most adenovirus infections are self-limiting in immunocompetent individuals. Here, we report a case of adenovirus pneumonia in a 17-year-old immunocompetent male. He was admitted to our emergency room complaining of a febrile sense, cough, and diarrhea for four days. Crackles in the left lung and a high fever (40.7 °C) were revealed. Initial chest X-ray and computed tomography images showed consolidation in the left lung. We immediately started empirical antibiotic treatment, but his clinical symptoms and pneumonic consolidation in radiography had not improved by hospital day three. Because adenovirus was detected in his sputum using RT-PCR, he was administered Cidofovir. After 24 h of Cidofovir treatment, the symptoms and fever subsided, and the consolidation in his X-ray was significantly reduced by hospital day nine. The early administration of Cidofovir could be beneficial for the treatment of adenovirus infection in immunocompetent patients.

Original languageEnglish
Pages (from-to)215-218
Number of pages4
JournalRespiratory Medicine Case Reports
Volume26
DOIs
StatePublished - 1 Jan 2019

Bibliographical note

Publisher Copyright:
© 2019 The Authors

Keywords

  • Adenovirus
  • Cidofovir
  • Healthy
  • Immunocompetent
  • Pneumonia
  • Young adult

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