@article{b2d8182e7610476c92e1b7a76792d0ca,
title = "Acredinones A and B, voltage-dependent potassium channel inhibitors from the sponge-derived fungus Acremonium sp. F9A015",
abstract = "Two new benzophenones, acredinones A (1) and B (2), were isolated from a marine-sponge-associated Acremonium sp. fungus. Their chemical structures were elucidated on the interpretation of spectroscopic data. The structure of 1 was confirmed by palladium-catalyzed hydrogenation, followed by spectroscopic data analysis. Acredinones A (1) and B (2) inhibited the outward K+ currents of the insulin secreting cell line INS-1 with IC50 values of 0.59 and 1.0 μM, respectively.",
author = "Hiyoung Kim and Inho Yang and Ryu, {Shin Young} and Won, {Dong Hwan} and Giri, {Awadut G.} and Weihong Wang and Hyukjae Choi and Jungwook Chin and Dongyup Hahn and Eunhee Kim and Chulkyeong Han and Jihye Lee and Nam, {Sang Jip} and Ho, {Won Kyung} and Heonjoong Kang",
note = "Publisher Copyright: {\textcopyright} 2015 The American Chemical Society and American Society of Pharmacognosy.",
year = "2015",
month = mar,
day = "27",
doi = "10.1021/np5007586",
language = "English",
volume = "78",
pages = "363--367",
journal = "Journal of Natural Products",
issn = "0163-3864",
publisher = "American Chemical Society",
number = "3",
}
