Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice

Medicine & Life Sciences

• Adenosine Triphosphate 5%
• Antioxidants 5%
• Catalase 78%
• Cell Line 4%
• Cysteine 6%
• Diet 56%
• Electrons 5%
• Endoplasmic Reticulum Stress 15%
• Fats 10%
• Fatty Acids 5%
• Fatty Liver 87%
• Heat-Shock Proteins 7%
• Hep G2 Cells 7%
• Hepatocellular Carcinoma 5%
• High Fat Diet 13%
• Hydrogen Peroxide 6%
• Knockout Mice 43%
• Lipid Peroxidation 6%
• Lipids 4%
• Liver 14%
• Liver Diseases 5%
• Liver Mitochondrion 8%
• Melatonin 7%
• Mitochondrial DNA 7%
• Non-alcoholic Fatty Liver Disease 29%
• Obese Mice 100%
• Organelle Biogenesis 8%
• Oxidative Stress 59%
• Therapeutics 2%

Chemical Compounds

• Ablation 94%
• Antioxidant Agent 5%
• Cysteine 6%
• Electron Particle 3%
• Fat 14%
• Hydrogen Peroxide 5%
• Lipid 10%
• Marker 6%
• Melatonin 9%
• Metabolic 6%
• Oxidative Stress 81%
• Protein 3%