A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Xiaoqiang Chen; Kyung Ah Lee; Eun Mi Ha; Kyung Mi Lee; You Yeong Seo; Han Kyoung Choi; Ha Na Kim; Min Jung Kim; Chun Seok Cho; Soo Young Lee; Won Jae Lee; Juyoung Yoon

doi:10.1039/c1cc10589b

A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Xiaoqiang Chen
, Kyung Ah Lee
, Eun Mi Ha
, Kyung Mi Lee
, You Yeong Seo
, Han Kyoung Choi
, Ha Na Kim
, Min Jung Kim
, Chun Seok Cho
, Soo Young Lee
, Won Jae Lee
, Juyoung Yoon

Research output: Contribution to journal › Article › peer-review

242 Scopus citations

Abstract

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

Original language	English
Pages (from-to)	4373-4375
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	15
DOIs	https://doi.org/10.1039/c1cc10589b
State	Published - 29 Mar 2011

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title = "A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production",

abstract = "A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.",

author = "Xiaoqiang Chen and Lee, \{Kyung Ah\} and Ha, \{Eun Mi\} and \{Mi Lee\}, Kyung and Seo, \{You Yeong\} and Choi, \{Han Kyoung\} and Kim, \{Ha Na\} and Kim, \{Min Jung\} and Cho, \{Chun Seok\} and Lee, \{Soo Young\} and Lee, \{Won Jae\} and Juyoung Yoon",

year = "2011",

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day = "29",

doi = "10.1039/c1cc10589b",

language = "English",

volume = "47",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

AU - Chen, Xiaoqiang

AU - Lee, Kyung Ah

AU - Ha, Eun Mi

AU - Mi Lee, Kyung

AU - Seo, You Yeong

AU - Choi, Han Kyoung

AU - Kim, Ha Na

AU - Kim, Min Jung

AU - Cho, Chun Seok

AU - Lee, Soo Young

AU - Lee, Won Jae

AU - Yoon, Juyoung

PY - 2011/3/29

Y1 - 2011/3/29

N2 - A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

AB - A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

UR - https://www.scopus.com/pages/publications/79954997251

U2 - 10.1039/c1cc10589b

DO - 10.1039/c1cc10589b

M3 - Article

C2 - 21399827

AN - SCOPUS:79954997251

SN - 1359-7345

VL - 47

SP - 4373

EP - 4375

JO - Chemical Communications

JF - Chemical Communications

IS - 15

ER -

A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Abstract

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