A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Xiaoqiang Chen, Kyung Ah Lee, Eun Mi Ha, Kyung Mi Lee, You Yeong Seo, Han Kyoung Choi, Ha Na Kim, Min Jung Kim, Chun Seok Cho, Soo Young Lee, Won Jae Lee, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

231 Scopus citations

Abstract

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

Original languageEnglish
Pages (from-to)4373-4375
Number of pages3
JournalChemical Communications
Volume47
Issue number15
DOIs
StatePublished - 29 Mar 2011

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