A selective 'Off-On' fluorescent sensor for Zn2+ based on hydrazone-pyrene derivative and its application for imaging of intracellular Zn2+

Ying Zhou, Ha Na Kim, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

91 Scopus citations

Abstract

A simple and effective fluorescent sensor based on hydrazone-pyrene has been synthesized. This probe displays a highly selective fluorescent enhancement with Zn2+, and application of this probe to detect the intrinsic Zn2+ ions present in pancreatic β-cells was successfully demonstrated.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume20
Issue number1
DOIs
StatePublished - 1 Jan 2010

Keywords

  • Fluorescent chemosensor
  • Fluorescent probe
  • Pyrene
  • Zinc sensor

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