@inproceedings{b0a585cdf48e44a69bd79baabf175b56,
title = "A resettable high-density microfluidic cell trapping system",
abstract = "Dynamic cell-based microarrays offer numerous benefits for biological applications such as cytokine detection, medical diagnostics, drug screening, and cellomics; however, current cell arraying techniques remain limited in terms of trapping density and device resettability. Here we demonstrate a resettable cell arraying system by utilizing simple geometric designs in microfluidic devices to manipulate microscale hydrodynamics. We show that arrays of individual bovine aortic endothelial cells (BAECs): (i) immobilize in designated trapping positions between microposts under forward fluidic flow, and (ii) release from the trapping sites under backward fluidic flow of 0.5X trypsin to reset the arrays.",
keywords = "Cell arraying, Cell trapping, Cell-based microarrays, Microparticle arraying",
author = "Sochol, {Ryan D.} and Kosuke Iwai and Higa, {Adrienne T.} and Lo, {Joanne C.} and Eric Zhou and Liana Lo and Chris Luong and Megan Dueck and Song Li and Lee, {Luke P.} and Liwei Lin",
year = "2010",
language = "English",
isbn = "9781618390622",
series = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
pages = "1574--1576",
booktitle = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
note = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 ; Conference date: 03-10-2010 Through 07-10-2010",
}