A multiplexed bioelectronic sensor was developed for the purpose of rapid, on-site, and simultaneous detection of various target molecules. Olfactory and taste receptors were produced in Escherichia coli, and the reconstituted receptors were immobilized onto a multi-channel type carbon nanotube field-effect transistor. This device mimicked the human olfactory/taste system and simultaneously measured the conductance changes with high sensitivity and selectivity following treatment with various odor and taste molecules commonly known to be indicators of food contamination. Various pattern recognition of odorants and tastants was available with a customized platform for the simultaneous measurement of electrical signals. The simple portable bioelectronic device was suitable for efficient monitoring of food freshness and is expected to be used as a rapid on-site sensing platform with various applications.
Bibliographical noteFunding Information:
The authors thank Dr. Kyung Hyun Park for his support with the portable monitoring system from the THz Photonics Creative Research Center of the Electronics and Telecommunications Research Institute. This research was supported by the Public Welfare & Safety Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning ( 2014039771 ), the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) ( 2014053108 ) and the Center for Integrated Smart Sensors funded by the Ministry of Science, ICT & Future Planning as a Global Frontier Project ( CISS-2011-0031870 ). SH acknowledges the support from the NRF grants (H-GUARD 2013M3A6B2078961 , 2014M3A7B4051591 ).
© 2016 Elsevier B.V.
- Bioelectronic sensor
- Carbon nanotube
- Field-effect transistor
- Human olfactory receptor
- Human taste receptor