A novel plasminogen activator inhibitor-1 inhibitor, TM5441, protects against high-fat diet-induced obesity and adipocyte injury in mice

Medicine and Dentistry

• Diet Induced Obesity 100%
• Injury 100%
• Adipocyte 100%
• High Fat Food 100%
• Plasminogen Activator Inhibitor-1 100%
• Therapeutic Agent 28%
• Insulin Resistance 28%
• Water-Electrolyte Imbalance 28%
• Insulin Sensitivity 14%
• down Regulation 14%
• Macrophage 14%
• Metabolic Syndrome 14%
• Feeding 14%
• Inflammatory Cytokine 14%
• Chronic Disease 14%
• Mitochondrial Biogenesis 14%
• Metabolic Stress 14%
• Inducible Nitric Oxide Synthase 14%
• Body Weight Gain 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Plasminogen Activator Inhibitor 1 100%
• Diet Induced Obesity 100%
• Injury 100%
• Metabolic Disorder 40%
• Insulin Resistance 40%
• Knockout Mouse 20%
• C57BL 6 Mouse 20%
• Cytokine 20%
• Metabolic Syndrome X 20%
• Inducible Nitric Oxide Synthase 20%
• Chronic Disease 20%
• Metabolic Stress 20%
• Inflammation 20%

Biochemistry, Genetics and Molecular Biology

• Adipocyte 100%
• Plasminogen Activator Inhibitor-1 100%
• Metabolic Disorder 40%
• Insulin Resistance 40%
• Macrophage 20%
• Knockout Mouse 20%
• Insulin Sensitivity 20%
• Proinflammatory Cytokine 20%
• Body Weight Gain 20%
• C57BL 6 Mouse 20%
• down Regulation 20%
• Mitochondrial Biogenesis 20%
• Blood Plasma 20%
• Nitric Oxide Synthase 20%