A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

Yutao Yang, Fangjun Huo, Caixia Yin, Ming Xu, Ying Hu, Jianbin Chao, Yongbin Zhang, Timothy E. Glass, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.

Original languageEnglish
Pages (from-to)5101-5104
Number of pages4
JournalJournal of Materials Chemistry B
Volume4
Issue number30
DOIs
StatePublished - 2016

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