A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

Yutao Yang; Fangjun Huo; Caixia Yin; Ming Xu; Ying Hu; Jianbin Chao; Yongbin Zhang; Timothy E. Glass; Juyoung Yoon

doi:10.1039/c6tb01392a

A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

Yutao Yang, Fangjun Huo, Caixia Yin, Ming Xu, Ying Hu, Jianbin Chao, Yongbin Zhang, Timothy E. Glass, Juyoung Yoon

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.

Original language	English
Pages (from-to)	5101-5104
Number of pages	4
Journal	Journal of Materials Chemistry B
Volume	4
Issue number	30
DOIs	https://doi.org/10.1039/c6tb01392a
State	Published - 2016

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© The Royal Society of Chemistry 2016.

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title = "A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition",

abstract = "The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.",

author = "Yutao Yang and Fangjun Huo and Caixia Yin and Ming Xu and Ying Hu and Jianbin Chao and Yongbin Zhang and Glass, {Timothy E.} and Juyoung Yoon",

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year = "2016",

doi = "10.1039/c6tb01392a",

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T1 - A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

AU - Yang, Yutao

AU - Huo, Fangjun

AU - Yin, Caixia

AU - Xu, Ming

AU - Hu, Ying

AU - Chao, Jianbin

AU - Zhang, Yongbin

AU - Glass, Timothy E.

AU - Yoon, Juyoung

PY - 2016

Y1 - 2016

N2 - The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.

AB - The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.

UR - http://www.scopus.com/inward/record.url?scp=84980008534&partnerID=8YFLogxK

U2 - 10.1039/c6tb01392a

DO - 10.1039/c6tb01392a

M3 - Article

AN - SCOPUS:84980008534

SN - 2050-7518

VL - 4

SP - 5101

EP - 5104

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 30

ER -

A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

Abstract

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