TY - JOUR
T1 - A new cytotoxic phenylbutenoid dimer from the rhizomes of Zingiber cassumunar
AU - Han, Ah Reum
AU - Min, Hye Young
AU - Windono, Tri
AU - Jeohn, Cwang Ho
AU - Jang, Dae Sik
AU - Lee, Sang Kook
AU - Seo, Eun Kyoung
PY - 2004/11
Y1 - 2004/11
N2 - A new phenylbutenoid dimer, (±)-trans-3-(4-hydroxy-3-methoxyphenyl)- 4-[(E)-3,4-dimethoxystyryl]cyclohex-1-ene, was isolated from the rhizomes of Zingiber cassumunar along with the three known compounds, (±)-trans-3-(3, 4-dimethoxyphenyl)-4-[(E)-3,4-dimethoxystyryl]cyclohex-1-ene, 4-(3,4-dimethoxyphenyl)but-1,3-diene, and 4-(2,4,5-trimethoxyphenyl)but-1,3- diene by bioassay-directed fractionation using the A549 human cancer cell line cytotoxicity assay. Structure of the new compound was elucidated by spectral analysis, including ID and 2D NMR experiments.
AB - A new phenylbutenoid dimer, (±)-trans-3-(4-hydroxy-3-methoxyphenyl)- 4-[(E)-3,4-dimethoxystyryl]cyclohex-1-ene, was isolated from the rhizomes of Zingiber cassumunar along with the three known compounds, (±)-trans-3-(3, 4-dimethoxyphenyl)-4-[(E)-3,4-dimethoxystyryl]cyclohex-1-ene, 4-(3,4-dimethoxyphenyl)but-1,3-diene, and 4-(2,4,5-trimethoxyphenyl)but-1,3- diene by bioassay-directed fractionation using the A549 human cancer cell line cytotoxicity assay. Structure of the new compound was elucidated by spectral analysis, including ID and 2D NMR experiments.
UR - http://www.scopus.com/inward/record.url?scp=9744249443&partnerID=8YFLogxK
U2 - 10.1055/s-2004-832656
DO - 10.1055/s-2004-832656
M3 - Article
C2 - 15549671
AN - SCOPUS:9744249443
SN - 0032-0943
VL - 70
SP - 1095
EP - 1097
JO - Planta Medica
JF - Planta Medica
IS - 11
ER -