TY - JOUR
T1 - A new C2-symmetric chiral bisphosphine ligand containing a bioxazole backbone
T2 - Highly enantioselective hydrosilylation of ketones
AU - Lee, Sang Gi
AU - Lim, Chung Woo
AU - Song, Choong Eui
AU - Kim, O.
N1 - Funding Information:
This research was supported by a grant from the Ministry of Science and Technology in Korea.
PY - 1997/12/23
Y1 - 1997/12/23
N2 - C2-Symmetric (4S,4'S)-2,2'-bis(o-diphenylphosphinophenyl-4,4',5,5'-tetrahydro-4,4'-bi(1,3 -oxazole) (1, Phos-Biox) has been designed and synthesized as a chiral ligand for metal-catalyzed reactions. The Phos-Biox 1 was found to be an efficient ligand for rhodium(I)-catalyzed asymmetric reduction of prochiral acetophenones with diphenylsilane to give optically active secondary alcohols of up to 97% ee.
AB - C2-Symmetric (4S,4'S)-2,2'-bis(o-diphenylphosphinophenyl-4,4',5,5'-tetrahydro-4,4'-bi(1,3 -oxazole) (1, Phos-Biox) has been designed and synthesized as a chiral ligand for metal-catalyzed reactions. The Phos-Biox 1 was found to be an efficient ligand for rhodium(I)-catalyzed asymmetric reduction of prochiral acetophenones with diphenylsilane to give optically active secondary alcohols of up to 97% ee.
UR - http://www.scopus.com/inward/record.url?scp=0031584574&partnerID=8YFLogxK
U2 - 10.1016/S0957-4166(97)00554-5
DO - 10.1016/S0957-4166(97)00554-5
M3 - Article
AN - SCOPUS:0031584574
SN - 0957-4166
VL - 8
SP - 4027
EP - 4031
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 24
ER -