As a new strategy for the optimization of a chiral catalyst, the catalytic activity of the host-guest complexes of chiral bisphosphine bearing imidazolidinone was investigated in Rh-catalyzed asymmetric hydrogenation of enamide. Marginal enhancement in enantioselectivity was observed and the nature of interaction between host-guest was experimentally elucidated.
|Number of pages||4|
|Journal||Bulletin of the Korean Chemical Society|
|State||Published - Mar 2010|
- Catalyst optimization
- Chiral catalyst