A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.

Inho Yang; Hyukjae Choi; Sang Jip Nam; Heonjoong Kang

doi:10.1007/s12272-015-0620-9

A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.

Inho Yang, Hyukjae Choi, Sang Jip Nam, Heonjoong Kang

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 μg ml^-1, respectively.

Original language	English
Pages (from-to)	1970-1974
Number of pages	5
Journal	Archives of Pharmacal Research
Volume	38
Issue number	11
DOIs	https://doi.org/10.1007/s12272-015-0620-9
State	Published - 1 Nov 2015

Bibliographical note

Publisher Copyright:
© 2015 The Pharmaceutical Society of Korea.

Keywords

Antibacterial
Ircinia
Marine natural product
Secosterol
Sponge

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10.1007/s12272-015-0620-9

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abstract = "An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 μg ml-1, respectively.",

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AU - Nam, Sang Jip

AU - Kang, Heonjoong

PY - 2015/11/1

Y1 - 2015/11/1

N2 - An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 μg ml-1, respectively.

AB - An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 μg ml-1, respectively.

KW - Antibacterial

KW - Ircinia

KW - Marine natural product

KW - Secosterol

KW - Sponge

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SN - 0253-6269

VL - 38

SP - 1970

EP - 1974

JO - Archives of Pharmacal Research

JF - Archives of Pharmacal Research

IS - 11

ER -

A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.

Abstract

Bibliographical note

Keywords

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