@article{b0781104b28e4354b735dcb1e392cfaa,
title = "A large kinetic isotope effect in the reaction of ascorbic acid with 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO˙) in aqueous buffer solutions",
abstract = "A large kinetic isotope effect (KIE,kH/kD) of 12.8 was observed for the hydrogen-transfer reaction from ascorbic acid to 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO˙) in a phosphate buffer solution (0.05 M, pH/pD 7.0) at 298 K. The isotopic difference in the activation energies (6.8 kJ mol−1) determined from the temperature dependence of the KIE suggests that quantum mechanical tunneling may partly play a role in the reaction, although the isotopic ratio of the Arrhenius prefactor (AH/AD= 0.86) is within the semiclassical limits.",
author = "Ikuo Nakanishi and Yoshimi Shoji and Kei Ohkubo and Toshihiko Ozawa and Matsumoto, {Ken Ichiro} and Shunichi Fukuzumi",
note = "Funding Information: This work was partially supported by Grant-in-Aid (No. 18K06620 to I. N., 20H02779, 20H04819, 18H04650, 17H03010 and 16H02268 to K. O.) from the Ministry of Education, Culture, Sports, Science and Technology, Japan. We also thank Dr Hiroaki Kotani (University of Tsukuba) for valuable discussions. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2020.",
year = "2020",
month = oct,
day = "4",
doi = "10.1039/d0cc05214k",
language = "English",
volume = "56",
pages = "11505--11507",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "77",
}