A hybrid approach to combine HMM and SVM methods for the prediction of the transmembrane spanning region

Min Kyung Kim, Chul Hwan Song, Seong Joon Yoo, Sang Ho Lee, Hyun Seok Park

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Transmembrane proteins are the primary targets for the development of new drugs, and a number of algorithms that predict transmembrane topology are publicly available on the Web. In this paper, we present a novel approach using both SVM and HMM methods and we demonstrate that our system outperform the previous systems which only use either HMM methods or SVM methods alone.

Original languageEnglish
Title of host publicationKnowledge-Based Intelligent Information and Engineering Systems - 9th International Conference, KES 2005, Proceedings
PublisherSpringer Verlag
Pages792-798
Number of pages7
ISBN (Print)3540288961, 9783540288961
DOIs
StatePublished - 2005
Event9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005 - Melbourne, Australia
Duration: 14 Sep 200516 Sep 2005

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume3683 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005
Country/TerritoryAustralia
CityMelbourne
Period14/09/0516/09/05

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