@article{4ee27d91317347f1a3e42076372d52ac,
title = "A histone H1-binding-aptide-based apoptosis imaging probe for monitoring tumor responses to cancer therapy",
abstract = "Here we report the feasibility of using a high-affinity histone H1-binding peptide as a potential molecular apoptosis imaging probe. The Cy5.5-labeled peptide showed high selectivity for drug-treated apoptotic tumors compared with non-apoptotic tumors in various in vivo settings, enabling detection of tumor responses to both docetaxel chemotherapy and Herceptin antibody therapy as early as 12 hours after treatment with a high signal-to-background ratio, even at extremely low doses.",
author = "Yonghyun Lee and Sunghyun Kim and Daejin Kim and Sangyong Jon",
note = "Funding Information: This work was supported by the Global Research Laboratory grant (2015045887) and the Radiation Technology R&D program (2014033231) through the National Research Foundation of Korea (NRF), funded by the Ministry of Science, ICT & Future Planning. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2017",
doi = "10.1039/c6md00696e",
language = "English",
volume = "8",
pages = "390--393",
journal = "MedChemComm",
issn = "2040-2503",
publisher = "Royal Society of Chemistry",
number = "2",
}