A highly sensitive and selective turn-on fluorogenic and chromogenic sensor based on BODIPY-functionalized magnetic nanoparticles for detecting lead in living cells

Hyunjong Son; Hye Young Lee; Jung Mi Lim; Dongmin Kang; Won Seok Han; Shim Sung Lee; Jong Hwa Jung

doi:10.1002/chem.201001772

A highly sensitive and selective turn-on fluorogenic and chromogenic sensor based on BODIPY-functionalized magnetic nanoparticles for detecting lead in living cells

Hyunjong Son, Hye Young Lee, Jung Mi Lim, Dongmin Kang, Won Seok Han, Shim Sung Lee, Jong Hwa Jung

Department of Life Science

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe ₃O₄@SiO₂ core/shell nanoparticles 1 has been prepared. Chemosensor 1 exhibits a high affinity and selectivity for Pb ²⁺ over competing metal ions tested. Moreover, confocal microscopy, and flow cytometry experiments established that 1 can be used for detecting Pb²⁺ levels within living cell.

Original language	English
Pages (from-to)	11549-11553
Number of pages	5
Journal	Chemistry - A European Journal
Volume	16
Issue number	38
DOIs	https://doi.org/10.1002/chem.201001772
State	Published - 11 Oct 2010

Keywords

Chromophores
Fluorophores
Lead nanoparticles
Sensors

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10.1002/chem.201001772

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abstract = "A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O4@SiO2 core/shell nanoparticles 1 has been prepared. Chemosensor 1 exhibits a high affinity and selectivity for Pb 2+ over competing metal ions tested. Moreover, confocal microscopy, and flow cytometry experiments established that 1 can be used for detecting Pb2+ levels within living cell.",

keywords = "Chromophores, Fluorophores, Lead nanoparticles, Sensors",

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AU - Lee, Hye Young

AU - Lim, Jung Mi

AU - Kang, Dongmin

AU - Han, Won Seok

AU - Lee, Shim Sung

AU - Jung, Jong Hwa

PY - 2010/10/11

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AB - A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O4@SiO2 core/shell nanoparticles 1 has been prepared. Chemosensor 1 exhibits a high affinity and selectivity for Pb 2+ over competing metal ions tested. Moreover, confocal microscopy, and flow cytometry experiments established that 1 can be used for detecting Pb2+ levels within living cell.

KW - Chromophores

KW - Fluorophores

KW - Lead nanoparticles

KW - Sensors

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JF - Chemistry - A European Journal

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ER -

A highly sensitive and selective turn-on fluorogenic and chromogenic sensor based on BODIPY-functionalized magnetic nanoparticles for detecting lead in living cells

Abstract

Keywords

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