A Fluorescent Sensor for Dual-Channel Discrimination between Phosgene and a Nerve-Gas Mimic

Xin Zhou, Yiying Zeng, Chen Liyan, Xue Wu, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

161 Scopus citations

Abstract

The ability to analyze highly toxic chemical warfare agents (CWAs) and related chemicals in a rapid and precise manner is essential in order to alleviate serious threats to humankind and public security caused by unexpected terrorist attacks and industrial accidents. In this investigation, we designed a o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase. Moreover, this dye has been used to construct a portable kit that can be employed for real-time monitoring of DCP and phosgene in the field, both in a discriminatory manner, and in a simple and safe way.

Original languageEnglish
Pages (from-to)4729-4733
Number of pages5
JournalAngewandte Chemie - International Edition
Volume55
Issue number15
DOIs
StatePublished - 4 Apr 2016

Keywords

  • carbenes
  • fluorescence
  • nerve-gas mimics
  • phosgene
  • sensors

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