A Diabetes-Related Dietary Pattern Is Associated with Incident Diabetes in Obese Men in the Korean Genome Epidemiology Study

Hye Ah Lee, Nayeong Son, Won Kyung Lee, Hyesook Park

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6 Scopus citations


Diet plays an important role in both the development and management of diabetes. Objective: Using data from the Korean Genome Epidemiology Study, we assessed dietary patterns associated with the clinical indicators of diabetes. Methods: This study included 7255 subjects aged 40-69 y. Individuals with chronic diseases were excluded. The daily intakes of specific food items were assessed using a dish-based semiquantitative food-frequency questionnaire comprising 103 items; the food items were then grouped into 26 food groups. Dietary patterns were analyzed by the reduced rank regression method using glycated hemoglobin, the homeostasis model of insulin resistance, and fasting glucose concentrations as dependent variables.We investigated the associations between dietary patterns and incident diabetes using the Cox proportional hazards model. Results: During an 11.5-y follow-up, the incidence of diabetes was 11.8/1000 person-years. The dietary pattern related to selected biomarkers of diabetes was characterized by a relatively high intake of kimchi, beef, other meat, fish, and coffee in men and a high intake of rice, kimchi, and fruit in women. In men, the association of dietary patterns with incident diabetes was significant only in the obese group, and those in the top quartile of the dietary pattern score had a 1.72 times (95% CI: 1.15, 2.56 times) greater risk of incident diabetes than those in the bottom quartile. Conversely, dietary patterns in women were not associated with incident diabetes. Conclusion: Using reduced rank regression, we identified dietary patterns related to selected biomarkers of diabetes in a long-term study with follow-up data in Korea. J Nutr 2019;149:323-329.

Original languageEnglish
Pages (from-to)323-329
Number of pages7
JournalJournal of Nutrition
Issue number2
StatePublished - 1 Feb 2019

Bibliographical note

Funding Information:
Supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2017 R1D1A1B03028719), which had no role in the design, analysis, or writing of this manuscript. Author disclosures: HAL, NS, WKL, and HP, no conflicts of interest. Supplemental Figures 1 and 2 and Supplemental Tables 1–4 are available from the “Supplementary data” link in the online posting of the article and from the same link in the online table of contents at https://academic.oup.com/jn/. Address correspondence to HAL (e-mail: khyeah@naver.com) or HP (e-mail: hpark@ewha.ac.kr). Abbreviations used: HbA1c, glycated hemoglobin; KoGES, Korean Genome Epidemiology Study; RRR, reduced rank regression.

Publisher Copyright:
© 2019 American Society for Nutrition. All rights reserved.


  • diabetes
  • dietary patterns
  • prospective cohort study
  • reduced rank regression


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