A comprehensive overview and recent advances on polyhydroxyalkanoates (PHA) production using various organic waste streams

Rijuta Ganesh Saratale, Si Kyung Cho, Ganesh Dattatraya Saratale, Avinash A. Kadam, Gajanan S. Ghodake, Manu Kumar, Ram Naresh Bharagava, Gopalakrishnan Kumar, Dong Su Kim, Sikandar I. Mulla, Han Seung Shin

Research output: Contribution to journalReview articlepeer-review

191 Scopus citations

Abstract

Polyhydroxyalkanoates (PHA) are appealing as an important alternative to replace synthetic plastics owing to its comparable physicochemical properties to that of synthetic plastics, and biodegradable and biocompatible nature. This review gives an inclusive overview of the current research activities dealing with PHA production by utilizing different waste fluxes generated from food, milk and sugar processing industries. Valorization of these waste fluxes makes the process cost effective and practically applicable. Recent advances in the approaches adopted for waste treatment, fermentation strategies, and genetic engineering can give insights to the researchers for future direction of waste to bioplastics production. Lastly, synthesis and application of PHA-nanocomposites, research and development challenges, future perspectives for sustainable and cost-effective PHB production are also discussed. In addition, the review addresses the useful information about the opportunities and confines associated with the sustainable PHA production using different waste streams and their evaluation for commercial implementation within a biorefinery.

Original languageEnglish
Article number124685
JournalBioresource Technology
Volume325
DOIs
StatePublished - Apr 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd

Keywords

  • Metabolic engineering
  • PHA-nanocomposites
  • Polyhydroxyalkanoates (PHA)
  • Sugarcane molasses
  • Waste animal fats
  • Whey

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