TY - JOUR
T1 - A comprehensive overview and recent advances on polyhydroxyalkanoates (PHA) production using various organic waste streams
AU - Ganesh Saratale, Rijuta
AU - Cho, Si Kyung
AU - Dattatraya Saratale, Ganesh
AU - Kadam, Avinash A.
AU - Ghodake, Gajanan S.
AU - Kumar, Manu
AU - Naresh Bharagava, Ram
AU - Kumar, Gopalakrishnan
AU - Su Kim, Dong
AU - Mulla, Sikandar I.
AU - Seung Shin, Han
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/4
Y1 - 2021/4
N2 - Polyhydroxyalkanoates (PHA) are appealing as an important alternative to replace synthetic plastics owing to its comparable physicochemical properties to that of synthetic plastics, and biodegradable and biocompatible nature. This review gives an inclusive overview of the current research activities dealing with PHA production by utilizing different waste fluxes generated from food, milk and sugar processing industries. Valorization of these waste fluxes makes the process cost effective and practically applicable. Recent advances in the approaches adopted for waste treatment, fermentation strategies, and genetic engineering can give insights to the researchers for future direction of waste to bioplastics production. Lastly, synthesis and application of PHA-nanocomposites, research and development challenges, future perspectives for sustainable and cost-effective PHB production are also discussed. In addition, the review addresses the useful information about the opportunities and confines associated with the sustainable PHA production using different waste streams and their evaluation for commercial implementation within a biorefinery.
AB - Polyhydroxyalkanoates (PHA) are appealing as an important alternative to replace synthetic plastics owing to its comparable physicochemical properties to that of synthetic plastics, and biodegradable and biocompatible nature. This review gives an inclusive overview of the current research activities dealing with PHA production by utilizing different waste fluxes generated from food, milk and sugar processing industries. Valorization of these waste fluxes makes the process cost effective and practically applicable. Recent advances in the approaches adopted for waste treatment, fermentation strategies, and genetic engineering can give insights to the researchers for future direction of waste to bioplastics production. Lastly, synthesis and application of PHA-nanocomposites, research and development challenges, future perspectives for sustainable and cost-effective PHB production are also discussed. In addition, the review addresses the useful information about the opportunities and confines associated with the sustainable PHA production using different waste streams and their evaluation for commercial implementation within a biorefinery.
KW - Metabolic engineering
KW - PHA-nanocomposites
KW - Polyhydroxyalkanoates (PHA)
KW - Sugarcane molasses
KW - Waste animal fats
KW - Whey
UR - http://www.scopus.com/inward/record.url?scp=85099820511&partnerID=8YFLogxK
U2 - 10.1016/j.biortech.2021.124685
DO - 10.1016/j.biortech.2021.124685
M3 - Review article
C2 - 33508681
AN - SCOPUS:85099820511
SN - 0960-8524
VL - 325
JO - Bioresource Technology
JF - Bioresource Technology
M1 - 124685
ER -