A case of xanthoma disseminatum

Sook Hyun Bang, Jeong Hyun Shin, Hae Young Choi, Ki Bum Myung

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2 Scopus citations


Xanthoma disseminatum is a rare benign, normolipemic form of histiocytoxanthomatosis, affecting the skin and mucous membranes, frequently associated with diabetes insipidus. It occurs mainly in young to middle-aged adults. The cutaneous manifestations consist of hundreds of yellowish papules which symmetrically involve the trunk, face, and proximal extremities including flexures and folds. The histopathologic finding is a mixture of foamy cells, histiocytes, and inflammatory cells. We report a 6-year-old male who had disseminated asymptomatic yellowish papules and plaques on whole body including flexures since infancy. Histological examination showed infiltrating foamy cells with lymphocytes and histiocytes in upper dermis. He had normal lipid profiles and symptoms of polyuria or polydipsia were absent.

Original languageEnglish
Pages (from-to)518-520
Number of pages3
JournalKorean Journal of Dermatology
Issue number4
StatePublished - 1 Apr 2003


  • Xanthoma disseminatum


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