A case of recurrent toxocariasis presenting with urticaria

Min Hye Kim, Jae Woo Jung, Jae Woo Kwon, Tae Whan Kim, Sae Hoon Kim, Sang Heon Cho, Kyung Up Min, You Young Kim, Yoon Seok Chang

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Human toxocariasis is the most prevalent helminthiasis in Korea and other industrialized countries. The clinical features of toxocariasis are diverse, according to the involved organ. Typically, Toxocara spp. infection is easily treated with 400 mg albendazole twice a day for 5 days. However, we experienced a case of recurrent toxocariasis that was refractory to this standard therapy and presented with urticaria, an uncommon symptom in toxocariasis. A 35-year-old male visited our emergency room because of abdominal pain. He had recently consumed raw cow liver (3 weeks prior to presentation). Laboratory analyses revealed eosinophilia (1,612 cells/μL) and increased total IgE (3,060 IU/mL). Chest X-ray showed multiple lung nodules in both lungs, and computed tomography revealed multiple ground-glass opacities in both lungs and multiple tiny liver abscesses. Liver biopsy revealed an eosinophilic abscess. Enzyme-linked immunosorbent assay findings for Toxocara antigens were positive (optical density, 2.140), leading to a diagnosis of toxocariasis. We initiated a 5-day treatment with albendazole and prednisolone; however, 6 days after completing the treatment, the patient again experienced urticaria and severe itching that could not be controlled by antihistamines or hydrocortisone cream. A second bout of eosinophilia suggested recurring toxocariasis, for which we prescribed a second round of albendazole. Despite an initial improvement in his symptoms, the patient returned after 6 weeks complaining of abdominal pain for 6 hours, which was reminiscent of his first attack; he also exhibited eosinophilia. Accordingly, albendazole was administered once more for an additional 3 weeks, and his symptoms resolved.

Original languageEnglish
Pages (from-to)267-270
Number of pages4
JournalAllergy, Asthma and Immunology Research
Issue number4
StatePublished - Oct 2010


  • Abdominal pain
  • Albendazole
  • Toxocariasis
  • Urticaria


Dive into the research topics of 'A case of recurrent toxocariasis presenting with urticaria'. Together they form a unique fingerprint.

Cite this