A case of primary antiphospholipid syndrome with pulmonary thromboembolism

Beom Lee Jae, Su Sim Yun, Wook Noh Young, Sung Park Hye, Hyun Tae Chung, Yeon Lim So, Hee Jun Yoon, Ju Ryu Yon, Mi Chun Eun, Hwa Lee Jin, Hyun Chang Jung, Wook Moon Jin

Research output: Contribution to journalArticlepeer-review


Antiphospholipid syndrome (APS) causes recurrent thromboses and morbidity during pregnancy, including fetal loss. This malady is associated with the persistent presence of anticardiolipin antibody or lupus anticoagulant. The pulmonary manifestations of antiphospholipid syndrome include pulmonary thromboembolism, pulmonary hypertension, acute respiratory distress syndrome, etc. Pulmonary thromboembolism is often the initial manifestation of antiphospholipid syndrome and a timely diagnosis is critical due to the high mortality rate. We herein report on a 19-year-old man with pulmonary thromboembolism that was caused by primary antiphospholipid syndrome. He presented with blood-tinged sputum, fever and epigastric pain, and his chest computerized tomography showed pulmonary thromboembolism. The other possible causes of pulmonary thromboembolism were excluded and the diagnosis of primary antiphospholipid syndrome was confirmed by the lupus anticoagulant that was present on two occasions six weeks apart. We also discuss the nature and management of antiphospholipid syndrome, along with a brief review of the relevant literatures.

Original languageEnglish
Pages (from-to)72-77
Number of pages6
JournalTuberculosis and Respiratory Diseases
Issue number1
StatePublished - Jul 2007


  • Antiphospholipid syndrome
  • Pulmonary thromboembolism
  • Thrombosis


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