A Case of Hepatocellular Carcinoma Presenting as a Gingival Mass

Min Jung Kwon, Soo Hyung Ryu, Soo Yeon Jo, Chul Hoon Kwak, Won Jae Yoon, Jeong Seop Moon, Hye Kyung Lee

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Oral metastatic tumor, which is uncommon and represents less than 1% of malignant oral neoplasms, usually arises from a primary mucosal or cutaneous cancer located in the head and neck regions. Metastasis of hepatocellular carcinoma (HCC) to the oral cavity, especially to gingiva, is extremely rare. A 50-year-old man, who was a chronic alcoholic and hepatitis B virus carrier, presented with abdominal distension and weight loss for the past 3 months. Three-phased contrast-enhanced abdominal CT revealed numerous conglomerated masses in the liver, suggesting huge HCCs arising in the background of liver cirrhosis with a large amount of ascites. He complained of recurrent profuse bleeding from the left upper gingival mass. A facial CT revealed an oral cavity mass destructing the left maxillary alveolar process and hard palate, which was diagnosed as metastatic HCC by an incisional biopsy. Herein, we report a case of metastatic HCC to the gingiva.

Original languageEnglish
Pages (from-to)321-325
Number of pages5
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Issue number6
StatePublished - 25 Dec 2016


  • Gingiva
  • Hepatocellular carcinoma
  • Mouth
  • Neoplasm metastasis


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