A Case of Cutaneous Focal Mucinosis with Onychomycosis

So Young Kim, Ji Sook Kim, Myung Hwa Kim, Hae Young Choi, Ki Bum Myung

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Cutaneous focal mucinosis was first described by Johnson and Helwig in 1961 and is histologically characterized by localized accumulation of mucin in the upper and middermis with scattered spindle-shaped fibroblasts. The mucin is jelly-like acid mucopolysaccharide consisting of hyaluronic acid bound to small amounts of chondroitin sulfate and heparin. The pathogenesis of cutaneous mucinosis is unclear. However, studies of various cutaneous mucinoses suggest that there may be an unknown circulating factor that stimulates fibroblasts to produce this material. Differential diagnoses include papular mucinosis, myxoid cyst, cutaneous myxoma. Simple surgical excision is the treatment of choice. In the present case, cutaneous focal mucinosis occurs on the nail bed with onychomycosis.

Original languageEnglish
Pages (from-to)61-64
Number of pages4
JournalKorean Journal of Dermatology
Issue number1
StatePublished - Jan 2004


  • Cutaneous focal mucinosis
  • Onychomycosis


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