A biomimetic ferric hydroperoxo porphyrin intermediate

Sam P. De Visser, Joan Selverstone Valentine, Wonwoo Nam

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


"Chemical Equation Presented" OOH, my! The protonation of a side-on high-spin ferric peroxo species yields the corresponding end-on low-spin ferric hydroperoxo intermediate (see picture), which is a precursor of Compound I and has been frequently proposed as a reactive species in heme enzymes. This ferric hydroperoxo complex can be used to study reactivities of similar species in substrate oxygenation and hydroperoxide O-O bond cleavage reactions.

Original languageEnglish
Pages (from-to)2099-2101
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number12
StatePublished - 15 Mar 2010


  • Bioinorganic chemistry
  • Ferric hydroperoxo complexes
  • Heme proteins
  • Oxygen activation
  • Porphyrinoids


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