A 1-50 GHz dielectric spectroscopy biosensor with integrated receiver front-end in 65nm CMOS

Jun Chau Chien, Mekhail Anwar, Erh Chia Yeh, Luke P. Lee, Ali M. Niknejad

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

36 Scopus citations

Abstract

In this paper, an on-chip transmission-line sensor with integrated receiver front-end implemented in 65nm CMOS facilitates the measurement of complex permittivity from 1 to 50 GHz for liquid samples. A robust extraction model allows accurate prediction of sample permittivity based on reference liquid calibration and eases the design of the hardware. Front-end circuits include a 60 GHz distributed amplifier with noise-cancellation active termination to improve the noise figure below 18 GHz. Correlated-double-sampling technique is used in the measurement setup to reject system phase drift. The sensor achieves 1% permittivity sensitivity at 20 GHz through liquid measurements with a minimum sensing volume of 0.09 nL. The prototype chip consumes a total power of 114 mW.

Original languageEnglish
Title of host publication2013 IEEE MTT-S International Microwave Symposium Digest, MTT 2013
DOIs
StatePublished - 2013
Event2013 IEEE MTT-S International Microwave Symposium Digest, MTT 2013 - Seattle, WA, United States
Duration: 2 Jun 20137 Jun 2013

Publication series

NameIEEE MTT-S International Microwave Symposium Digest
ISSN (Print)0149-645X

Conference

Conference2013 IEEE MTT-S International Microwave Symposium Digest, MTT 2013
Country/TerritoryUnited States
CitySeattle, WA
Period2/06/137/06/13

Keywords

  • Coplanar waveguide
  • Correlated-double-sampling
  • Distributed amplifier
  • Microfluidics
  • Noise-cancellation
  • Permittivity measurement

Fingerprint

Dive into the research topics of 'A 1-50 GHz dielectric spectroscopy biosensor with integrated receiver front-end in 65nm CMOS'. Together they form a unique fingerprint.

Cite this