5-(4-Hydroxyphenethenyl)-4,7-dimethoxycoumarin, a new constituent of Monotes engleri

Eun Kyoung Seo, Hee Byung Chai, Tangai E. Chagwedera, Norman R. Farnsworth, Geoffrey A. Cordell, John M. Pezzuto, A. Douglas Kinghorn

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A new coumarin, 5-(4-hydroxyphenethenyl)-4,7-dimethoxycoumarin (1) was isolated from the combined ethyl acetate extracts of the root bark, root wood and stern bark of Monotes engleri, and found to be cytotoxic against two cell lines in a human tumor panel. Its structure was determined on the basis of spectroscopic methods.

Original languageEnglish
Pages (from-to)182-184
Number of pages3
JournalPlanta Medica
Issue number2
StatePublished - 2000


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