2,2-dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors

Song Seok Shin, Min Soo Noh, Young Joo Byun, Jin Kyu Choi, Ji Young Kim, Kyung Min Lim, Jun Yong Ha, Jin Kwan Kim, Chang Hoon Lee, Shin Chung

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

A series of 2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2).

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume11
Issue number2
DOIs
StatePublished - 22 Jan 2001

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