128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording

S. E. Lee; J. H. Byun; J. Jeong; J. H. Kim; S. H. Ahn; J. H. Park; K. S. Min; S. B. Jun; N. L. Jeon; S. J. Kim

128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording

S. E. Lee, J. H. Byun, J. Jeong, J. H. Kim, S. H. Ahn, J. H. Park, K. S. Min, S. B. Jun, N. L. Jeon, S. J. Kim

Electronic and Electrical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

For long-term applications of implantable neural probes, a drug-delivery system can be employed to improve the electrical recording/stimulus quality by means of releasing biochemical for reduction of tissue reactions. We report a 128-channel MEA with eight fiber-embedded microfluidic channels. The integration of a large number of electrodes on a flexible surface required an improved flattening method. To verify the feasibility of the proposed device, liquid transportation via microfluidic channels and multi-channel neural recordings were performed. The local field potential of a rodent brain was successfully recorded, and the water-fall analysis showed a constant flow rate in the microfluidic channels.

Original language	English
Title of host publication	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Publisher	Chemical and Biological Microsystems Society
Pages	2088-2090
Number of pages	3
ISBN (Electronic)	9780979806476
State	Published - 2014
Event	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014

Publication series

Name	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Conference

Conference	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Country/Territory	United States
City	San Antonio
Period	26/10/14 → 30/10/14

Bibliographical note

Publisher Copyright:
© 14CBMS.

Keywords

Hybrid electrode
Microfluidic channel
Multi-electrode arrays
Polymer electrode

Cite this

Lee, S. E., Byun, J. H., Jeong, J., Kim, J. H., Ahn, S. H., Park, J. H., Min, K. S., Jun, S. B., Jeon, N. L., & Kim, S. J. (2014). 128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 2088-2090). (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014). Chemical and Biological Microsystems Society.

Lee, S. E. ; Byun, J. H. ; Jeong, J. et al. / 128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. pp. 2088-2090 (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

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title = "128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording",

abstract = "For long-term applications of implantable neural probes, a drug-delivery system can be employed to improve the electrical recording/stimulus quality by means of releasing biochemical for reduction of tissue reactions. We report a 128-channel MEA with eight fiber-embedded microfluidic channels. The integration of a large number of electrodes on a flexible surface required an improved flattening method. To verify the feasibility of the proposed device, liquid transportation via microfluidic channels and multi-channel neural recordings were performed. The local field potential of a rodent brain was successfully recorded, and the water-fall analysis showed a constant flow rate in the microfluidic channels.",

keywords = "Hybrid electrode, Microfluidic channel, Multi-electrode arrays, Polymer electrode",

author = "Lee, {S. E.} and Byun, {J. H.} and J. Jeong and Kim, {J. H.} and Ahn, {S. H.} and Park, {J. H.} and Min, {K. S.} and Jun, {S. B.} and Jeon, {N. L.} and Kim, {S. J.}",

note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",

year = "2014",

language = "English",

series = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",

publisher = "Chemical and Biological Microsystems Society",

pages = "2088--2090",

booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",

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Lee, SE, Byun, JH, Jeong, J, Kim, JH, Ahn, SH, Park, JH, Min, KS, Jun, SB, Jeon, NL & Kim, SJ 2014, 128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording. in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, Chemical and Biological Microsystems Society, pp. 2088-2090, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, United States, 26/10/14.

128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording. / Lee, S. E.; Byun, J. H.; Jeong, J. et al.
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. p. 2088-2090 (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - 128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording

AU - Lee, S. E.

AU - Byun, J. H.

AU - Jeong, J.

AU - Kim, J. H.

AU - Ahn, S. H.

AU - Park, J. H.

AU - Min, K. S.

AU - Jun, S. B.

AU - Jeon, N. L.

AU - Kim, S. J.

PY - 2014

Y1 - 2014

N2 - For long-term applications of implantable neural probes, a drug-delivery system can be employed to improve the electrical recording/stimulus quality by means of releasing biochemical for reduction of tissue reactions. We report a 128-channel MEA with eight fiber-embedded microfluidic channels. The integration of a large number of electrodes on a flexible surface required an improved flattening method. To verify the feasibility of the proposed device, liquid transportation via microfluidic channels and multi-channel neural recordings were performed. The local field potential of a rodent brain was successfully recorded, and the water-fall analysis showed a constant flow rate in the microfluidic channels.

AB - For long-term applications of implantable neural probes, a drug-delivery system can be employed to improve the electrical recording/stimulus quality by means of releasing biochemical for reduction of tissue reactions. We report a 128-channel MEA with eight fiber-embedded microfluidic channels. The integration of a large number of electrodes on a flexible surface required an improved flattening method. To verify the feasibility of the proposed device, liquid transportation via microfluidic channels and multi-channel neural recordings were performed. The local field potential of a rodent brain was successfully recorded, and the water-fall analysis showed a constant flow rate in the microfluidic channels.

KW - Hybrid electrode

KW - Microfluidic channel

KW - Multi-electrode arrays

KW - Polymer electrode

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M3 - Conference contribution

AN - SCOPUS:84941730160

T3 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

SP - 2088

EP - 2090

BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

PB - Chemical and Biological Microsystems Society

T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Y2 - 26 October 2014 through 30 October 2014

ER -

Lee SE, Byun JH, Jeong J, Kim JH, Ahn SH, Park JH et al. 128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society. 2014. p. 2088-2090. (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

128-Channel flexible mea with drug delivery channels for in vivo nerve stimulation and recording

Abstract

Publication series

Conference

Bibliographical note

Keywords

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