111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Ji Young Lee; Woon Jeong Lee; Sung Eun Hur; Chul Min Lee; Yeon Ah Sung; Hye Won Chung

doi:10.1016/j.fertnstert.2008.06.023

111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Ji Young Lee
, Woon Jeong Lee
, Sung Eun Hur
, Chul Min Lee
, Yeon Ah Sung
, Hye Won Chung

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

Original language	English
Pages (from-to)	830-833
Number of pages	4
Journal	Fertility and Sterility
Volume	92
Issue number	2
DOIs	https://doi.org/10.1016/j.fertnstert.2008.06.023
State	Published - Aug 2009

Bibliographical note

Funding Information:
Supported by Konkuk University in 2006.

Access to Document

10.1016/j.fertnstert.2008.06.023

Cite this

@article{4d544710a02f4f73a8107520aeef63e8,

title = "111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women",

abstract = "We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.",

author = "Lee, \{Ji Young\} and Lee, \{Woon Jeong\} and Hur, \{Sung Eun\} and Lee, \{Chul Min\} and Sung, \{Yeon Ah\} and Chung, \{Hye Won\}",

note = "Funding Information: Supported by Konkuk University in 2006. ",

year = "2009",

month = aug,

doi = "10.1016/j.fertnstert.2008.06.023",

language = "English",

volume = "92",

pages = "830--833",

journal = "Fertility and Sterility",

issn = "0015-0282",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - 111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

AU - Lee, Ji Young

AU - Lee, Woon Jeong

AU - Hur, Sung Eun

AU - Lee, Chul Min

AU - Sung, Yeon Ah

AU - Chung, Hye Won

N1 - Funding Information: Supported by Konkuk University in 2006.

PY - 2009/8

Y1 - 2009/8

N2 - We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

AB - We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

UR - https://www.scopus.com/pages/publications/67651099079

U2 - 10.1016/j.fertnstert.2008.06.023

DO - 10.1016/j.fertnstert.2008.06.023

M3 - Article

C2 - 18701098

AN - SCOPUS:67651099079

SN - 0015-0282

VL - 92

SP - 830

EP - 833

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 2

ER -

111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Abstract

Bibliographical note

Access to Document

Fingerprint

Cite this