111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Ji Young Lee, Woon Jeong Lee, Sung Eun Hur, Chul Min Lee, Yeon Ah Sung, Hye Won Chung

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

Original languageEnglish
Pages (from-to)830-833
Number of pages4
JournalFertility and Sterility
Volume92
Issue number2
DOIs
StatePublished - Aug 2009

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