111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Ji Young Lee; Woon Jeong Lee; Sung Eun Hur; Chul Min Lee; Yeon Ah Sung; Hye Won Chung

doi:10.1016/j.fertnstert.2008.06.023

111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Ji Young Lee, Woon Jeong Lee, Sung Eun Hur, Chul Min Lee, Yeon Ah Sung, Hye Won Chung

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

Original language	English
Pages (from-to)	830-833
Number of pages	4
Journal	Fertility and Sterility
Volume	92
Issue number	2
DOIs	https://doi.org/10.1016/j.fertnstert.2008.06.023
State	Published - Aug 2009

Bibliographical note

Funding Information:
Supported by Konkuk University in 2006.

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title = "111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women",

abstract = "We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.",

author = "Lee, {Ji Young} and Lee, {Woon Jeong} and Hur, {Sung Eun} and Lee, {Chul Min} and Sung, {Yeon Ah} and Chung, {Hye Won}",

note = "Funding Information: Supported by Konkuk University in 2006. ",

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doi = "10.1016/j.fertnstert.2008.06.023",

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journal = "Fertility and Sterility",

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T1 - 111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

AU - Lee, Ji Young

AU - Lee, Woon Jeong

AU - Hur, Sung Eun

AU - Lee, Chul Min

AU - Sung, Yeon Ah

AU - Chung, Hye Won

N1 - Funding Information: Supported by Konkuk University in 2006.

PY - 2009/8

Y1 - 2009/8

N2 - We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

AB - We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population.

UR - http://www.scopus.com/inward/record.url?scp=67651099079&partnerID=8YFLogxK

U2 - 10.1016/j.fertnstert.2008.06.023

DO - 10.1016/j.fertnstert.2008.06.023

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AN - SCOPUS:67651099079

SN - 0015-0282

VL - 92

SP - 830

EP - 833

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 2

ER -

111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Abstract

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